The 12 Best HIPAA Compliance Software in 2026
Ranked by real buyer interest on ISMS Directory over the last 30 days. Updated June 2026.
1. Vanta
AI-powered trust management platform that automates compliance, manages risk, and builds customer trust across 35+ frameworks.
- ISO 27001
- SOC 2
- GDPR
- HIPAA
- HITRUST
- ISO 42001
2. Strike Graph
AI-native compliance management platform that accelerates audits and eliminates redundant work across 5,000+ data source integrations.
- ISO 27001
- ISO 27701
- ISO 42001
- SOC 2
- GDPR
- HIPAA
3. LowerPlane
LowerPlane is a compliance automation platform that helps growing companies achieve SOC 2, ISO 27001, GDPR, and HIPAA faster — with continuous monitoring, policy automation, and custom review workflows.
- ISO 27001
- SOC 2 Type 2
- GDPR
- Multi-framework
- HIPAA
- PCI DSS
4. Scrut Automation
Scrut Automation simplifies continuous compliance automation for cloud-native companies.
- ISO 27001
- SOC 2
- GDPR
- HIPAA
- PCI DSS
- ISO 27701
5. Compleye
Compleye provides a user-friendly compliance platform to help companies achieve ISO 27001, SOC 2, ISO 9001, and GDPR compliance quickly and efficiently.
- ISO 27001
- ISO 9001
- SOC 2 Type 2
- GDPR
- ISO 27701
- HIPAA
6. Oneleet
Security-first compliance platform that consolidates penetration testing, code scanning, and compliance into one integrated solution.
- ISO 27001
- SOC 2
- GDPR
- HIPAA
- PCI DSS
- DORA
7. Anecdotes
Enterprise agentic GRC platform with 230+ integrations and 40+ pre-mapped frameworks for Fortune 500 compliance programs.
- ISO 27001
- ISO 27701
- ISO 42001
- ISO 22301
- SOC 2
- GDPR
8. Scytale
AI-powered compliance automation platform with dedicated human experts, supporting 60+ security and privacy frameworks.
- ISO 27001
- ISO 27701
- ISO 42001
- ISO 9001
- ISO 22301
- SOC 2
9. Secureframe
AI-powered GRC platform that automates compliance, mitigates risk, and builds customer trust through expert-backed automation.
- ISO 27001
- SOC 2
- GDPR
- HIPAA
- PCI DSS
- ISO 42001
10. Carbide
Canadian security and privacy management platform combining software automation with expert advisory for fast-growing companies.
- ISO 27001
- SOC 2
- GDPR
- HIPAA
- PCI DSS
- NIST CSF
11. EasyAudit
We help you achieve SOC 2 compliance for half the cost (using AI).
- SOC 2 Type 2
- ISO 27001
- ISO 42001
- HIPAA
- GDPR
- NIST CSF
12. Zerberus.ai
Zerberus.ai helps SaaS companies fast-track ISO 27001 & SOC 2 compliance in just 10 days using AI-driven automation, one-click remediation, and real-time risk mapping tailored to your tech stack.
- ISO 27001
- ISO 42001
- SOC 2 Type 2
- GDPR
- Multi-framework
- HIPAA
Frequently asked questions
- How is this HIPAA Compliance Software ranking determined?
- Providers are first filtered to those that substantively cover HIPAA Compliance Software in the ISMS Directory catalogue, then ordered by real buyer interest — the directory traffic and engagement each provider received over the last 30 days. It is not paid placement and it is not an editorial opinion.
- How often is the list updated?
- The ranking recomputes from live directory-demand data on a rolling 30-day window and refreshes roughly every 15 minutes, so it reflects current interest rather than a one-off 2026 snapshot.
- Why are only 12 providers shown?
- This list shows the top providers by demand for HIPAA Compliance Software. Pages with fewer than three substantively-matching providers are not published at all, so every entry here represents a real, comparable option.
- How can my company appear here?
- Get listed in ISMS Directory with HIPAA Compliance Software expertise. Ranking is earned through genuine directory demand — there is no way to pay for a position.