The 12 Best HIPAA Compliance Software in 2026

    Ranked by real buyer interest on ISMS Directory over the last 30 days. Updated September 2026.

    1. 1. LogicGate

      Chicago no-code GRC platform (Risk Cloud) for enterprise risk, compliance, and audit workflows.

      • HIPAA
      • SOC 2
      • ISO 27001
      • NIST CSF
      • Multi-framework
      • DORA
    2. 2. heygrc

      GitHub App that reviews every pull request against your compliance frameworks, flags changes that put a control at risk, and says exactly what to fix.

      • HIPAA
      • ISO 27001
      • SOC 2
      • GDPR
      • EU AI ACT
      • DORA
    3. 3. MetricStream

      Enterprise GRC suite for operational risk, compliance, audit, and third-party risk at large institutions.

      • HIPAA
      • SOX
      • ISO 27001
      • NIST CSF
      • Multi-framework
      • CCPA
    4. 4. OneTrust

      Atlanta GRC and privacy platform for privacy, third-party risk, and compliance programs at enterprise scale.

      • HIPAA
      • GDPR
      • CCPA
      • ISO 27001
      • SOC 2
      • EU AI ACT
    5. 5. Comp AI

      US open-source-friendly compliance automation platform for SOC 2, ISO 27001, and HIPAA evidence.

      • HIPAA
      • SOC 2
      • ISO 27001
      • GDPR
      • Multi-framework
    6. 6. Vanta

      AI-powered trust management platform that automates compliance, manages risk, and builds customer trust across 35+ frameworks.

      • HIPAA
      • ISO 27001
      • SOC 2
      • GDPR
      • HITRUST
      • ISO 42001
    7. 7. EasyAudit

      We help you achieve SOC 2 compliance for half the cost (using AI).

      • HIPAA
      • SOC 2 Type 2
      • ISO 27001
      • ISO 42001
      • GDPR
      • NIST CSF
    8. 8. Oneleet

      Security-first compliance platform that consolidates penetration testing, code scanning, and compliance into one integrated solution.

      • HIPAA
      • ISO 27001
      • SOC 2
      • GDPR
      • PCI DSS
      • DORA
    9. 9. Thoropass

      End-to-end compliance platform combining AI-powered automation with in-house audit services from Big 4 trained experts.

      • HIPAA
      • ISO 27001
      • ISO 42001
      • SOC 2
      • GDPR
      • HITRUST
    10. 10. Apptega

      Atlanta continuous-compliance platform built for MSSPs and security teams running multi-framework programs.

      • HIPAA
      • NIST CSF
      • CIS Controls
      • SOC 2
      • CMMC
      • Multi-framework
    11. 11. Ostendio

      Washington DC security and compliance platform for assessments, vendor risk, and control programs.

      • HIPAA
      • SOC 2
      • NIST CSF
      • CMMC
      • ISO 27001
      • Multi-framework
    12. 12. Scytale

      AI-powered compliance automation platform with dedicated human experts, supporting 60+ security and privacy frameworks.

      • HIPAA
      • ISO 27001
      • ISO 27701
      • ISO 42001
      • ISO 9001
      • ISO 22301

    Compare at a glance

    Same order as the ranked list above. Ranking reflects visitor interest measured on ISMS Directory over the last 30 days, not paid placement. Framework and region values come from the directory catalogue.
    RankProviderListed frameworksListed regionsProfile
    1LogicGateHIPAA, SOC 2, ISO 27001, NIST CSF, Multi-framework, DORAUnited States, GlobalView profile
    2heygrcHIPAA, ISO 27001, SOC 2, GDPR, EU AI ACT, DORAGlobalView profile
    3MetricStreamHIPAA, SOX, ISO 27001, NIST CSF, Multi-framework, CCPAUnited States, Global, AsiaView profile
    4OneTrustHIPAA, GDPR, CCPA, ISO 27001, SOC 2, EU AI ACTUnited States, Global, EuropeView profile
    5Comp AIHIPAA, SOC 2, ISO 27001, GDPR, Multi-frameworkUnited States, GlobalView profile
    6VantaHIPAA, ISO 27001, SOC 2, GDPR, HITRUST, ISO 42001GlobalView profile
    7EasyAuditHIPAA, SOC 2 Type 2, ISO 27001, ISO 42001, GDPR, NIST CSFCanada, Europe, Latin America +2 moreView profile
    8OneleetHIPAA, ISO 27001, SOC 2, GDPR, PCI DSS, DORAGlobalView profile
    9ThoropassHIPAA, ISO 27001, ISO 42001, SOC 2, GDPR, HITRUSTGlobalView profile
    10ApptegaHIPAA, NIST CSF, CIS Controls, SOC 2, CMMC, Multi-frameworkUnited States, GlobalView profile
    11OstendioHIPAA, SOC 2, NIST CSF, CMMC, ISO 27001, Multi-frameworkUnited States, GlobalView profile
    12ScytaleHIPAA, ISO 27001, ISO 27701, ISO 42001, ISO 9001, ISO 22301GlobalView profile

    Frequently asked questions

    How is this HIPAA Compliance Software ranking determined?
    Providers are first filtered to those that substantively cover HIPAA Compliance Software in the ISMS Directory catalogue, then ordered by real buyer interest — the directory traffic and engagement each provider received over the last 30 days. It is not paid placement and it is not an editorial opinion.
    How often is the list updated?
    The ranking recomputes from live directory-demand data on a rolling 30-day window and refreshes roughly every 15 minutes, so it reflects current interest rather than a one-off 2026 snapshot.
    Why are only 12 providers shown?
    This list shows the top providers by demand for HIPAA Compliance Software. Pages with fewer than three substantively-matching providers are not published at all, so every entry here represents a real, comparable option.
    How can my company appear here?
    Get listed in ISMS Directory with HIPAA Compliance Software expertise. Ranking is earned through genuine directory demand — there is no way to pay for a position.