The 12 Best HIPAA Compliance Software in 2026
Ranked by real buyer interest on ISMS Directory over the last 30 days. Updated September 2026.
1. LogicGate
Chicago no-code GRC platform (Risk Cloud) for enterprise risk, compliance, and audit workflows.
- HIPAA
- SOC 2
- ISO 27001
- NIST CSF
- Multi-framework
- DORA
2. heygrc
GitHub App that reviews every pull request against your compliance frameworks, flags changes that put a control at risk, and says exactly what to fix.
- HIPAA
- ISO 27001
- SOC 2
- GDPR
- EU AI ACT
- DORA
3. MetricStream
Enterprise GRC suite for operational risk, compliance, audit, and third-party risk at large institutions.
- HIPAA
- SOX
- ISO 27001
- NIST CSF
- Multi-framework
- CCPA
4. OneTrust
Atlanta GRC and privacy platform for privacy, third-party risk, and compliance programs at enterprise scale.
- HIPAA
- GDPR
- CCPA
- ISO 27001
- SOC 2
- EU AI ACT
5. Comp AI
US open-source-friendly compliance automation platform for SOC 2, ISO 27001, and HIPAA evidence.
- HIPAA
- SOC 2
- ISO 27001
- GDPR
- Multi-framework
6. Vanta
AI-powered trust management platform that automates compliance, manages risk, and builds customer trust across 35+ frameworks.
- HIPAA
- ISO 27001
- SOC 2
- GDPR
- HITRUST
- ISO 42001
7. EasyAudit
We help you achieve SOC 2 compliance for half the cost (using AI).
- HIPAA
- SOC 2 Type 2
- ISO 27001
- ISO 42001
- GDPR
- NIST CSF
8. Oneleet
Security-first compliance platform that consolidates penetration testing, code scanning, and compliance into one integrated solution.
- HIPAA
- ISO 27001
- SOC 2
- GDPR
- PCI DSS
- DORA
9. Thoropass
End-to-end compliance platform combining AI-powered automation with in-house audit services from Big 4 trained experts.
- HIPAA
- ISO 27001
- ISO 42001
- SOC 2
- GDPR
- HITRUST
10. Apptega
Atlanta continuous-compliance platform built for MSSPs and security teams running multi-framework programs.
- HIPAA
- NIST CSF
- CIS Controls
- SOC 2
- CMMC
- Multi-framework
11. Ostendio
Washington DC security and compliance platform for assessments, vendor risk, and control programs.
- HIPAA
- SOC 2
- NIST CSF
- CMMC
- ISO 27001
- Multi-framework
12. Scytale
AI-powered compliance automation platform with dedicated human experts, supporting 60+ security and privacy frameworks.
- HIPAA
- ISO 27001
- ISO 27701
- ISO 42001
- ISO 9001
- ISO 22301
Compare at a glance
| Rank | Provider | Listed frameworks | Listed regions | Profile |
|---|---|---|---|---|
| 1 | LogicGate | HIPAA, SOC 2, ISO 27001, NIST CSF, Multi-framework, DORA | United States, Global | View profile |
| 2 | heygrc | HIPAA, ISO 27001, SOC 2, GDPR, EU AI ACT, DORA | Global | View profile |
| 3 | MetricStream | HIPAA, SOX, ISO 27001, NIST CSF, Multi-framework, CCPA | United States, Global, Asia | View profile |
| 4 | OneTrust | HIPAA, GDPR, CCPA, ISO 27001, SOC 2, EU AI ACT | United States, Global, Europe | View profile |
| 5 | Comp AI | HIPAA, SOC 2, ISO 27001, GDPR, Multi-framework | United States, Global | View profile |
| 6 | Vanta | HIPAA, ISO 27001, SOC 2, GDPR, HITRUST, ISO 42001 | Global | View profile |
| 7 | EasyAudit | HIPAA, SOC 2 Type 2, ISO 27001, ISO 42001, GDPR, NIST CSF | Canada, Europe, Latin America +2 more | View profile |
| 8 | Oneleet | HIPAA, ISO 27001, SOC 2, GDPR, PCI DSS, DORA | Global | View profile |
| 9 | Thoropass | HIPAA, ISO 27001, ISO 42001, SOC 2, GDPR, HITRUST | Global | View profile |
| 10 | Apptega | HIPAA, NIST CSF, CIS Controls, SOC 2, CMMC, Multi-framework | United States, Global | View profile |
| 11 | Ostendio | HIPAA, SOC 2, NIST CSF, CMMC, ISO 27001, Multi-framework | United States, Global | View profile |
| 12 | Scytale | HIPAA, ISO 27001, ISO 27701, ISO 42001, ISO 9001, ISO 22301 | Global | View profile |
Frequently asked questions
- How is this HIPAA Compliance Software ranking determined?
- Providers are first filtered to those that substantively cover HIPAA Compliance Software in the ISMS Directory catalogue, then ordered by real buyer interest — the directory traffic and engagement each provider received over the last 30 days. It is not paid placement and it is not an editorial opinion.
- How often is the list updated?
- The ranking recomputes from live directory-demand data on a rolling 30-day window and refreshes roughly every 15 minutes, so it reflects current interest rather than a one-off 2026 snapshot.
- Why are only 12 providers shown?
- This list shows the top providers by demand for HIPAA Compliance Software. Pages with fewer than three substantively-matching providers are not published at all, so every entry here represents a real, comparable option.
- How can my company appear here?
- Get listed in ISMS Directory with HIPAA Compliance Software expertise. Ranking is earned through genuine directory demand — there is no way to pay for a position.
